Class I(A) Phosphoinositide 3-Kinase Regulates Heart Size and Physiological Cardiac Hypertrophy

Class I(A) phosphoinositide 3-kinases (PI3Ks) are activated by growth factor receptors, and they regulate, among other processes, cell growth and organ size. Studies using transgenic mice overexpressing constitutively active and dominant negative forms of the p110α catalytic subunit of class I(A) PI...

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Hlavní autoři: Luo, Ji, McMullen, Julie R., Sobkiw, Cassandra L., Zhang, Li, Dorfman, Adam L., Sherwood, Megan C., Logsdon, M. Nicole, Horner, James W., DePinho, Ronald A., Izumo, Seigo, Cantley, Lewis C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265829/
https://ncbi.nlm.nih.gov/pubmed/16227599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9491-9502.2005
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