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Transcription Factor GATA4 Is Activated but Not Required for Insulin-like Growth Factor 1 (IGF1)-induced Cardiac Hypertrophy

Insulin-like growth factor 1 (IGF1) promotes a physiological type of cardiac hypertrophy and has therapeutic effects in heart disease. Here, we report the relationship of IGF1 to GATA4, an essential transcription factor in cardiac hypertrophy and cell survival. In cultured neonatal rat ventricular m...

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Detalhes bibliográficos
Main Authors: Bisping, Egbert, Ikeda, Sadakatsu, Sedej, Miriam, Wakula, Paulina, McMullen, Julie R., Tarnavski, Oleg, Sedej, Simon, Izumo, Seigo, Pu, William T., Pieske, Burkert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323002/
https://ncbi.nlm.nih.gov/pubmed/22228770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.338749
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