Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure

An important event in the pathogenesis of heart failure is the development of pathological cardiac hypertrophy. In cultured cardiomyocytes, the transcription factor Gata4 is required for agonist-induced hypertrophy. We hypothesized that, in the intact organism, Gata4 is an important regulator of pos...

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Detalhes bibliográficos
Main Authors: Bisping, Egbert, Ikeda, Sadakatsu, Kong, Sek Won, Tarnavski, Oleg, Bodyak, Natalya, McMullen, Julie R., Rajagopal, Satish, Son, Jennifer K., Ma, Qing, Springer, Zhangli, Kang, Peter M., Izumo, Seigo, Pu, William T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636702/
https://ncbi.nlm.nih.gov/pubmed/16983087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602543103
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