Evolution of Relapse-Proficient Subclones Constrained by Collateral Sensitivity to Oncogene Overdose in Wnt-Driven Mammary Cancer

per Keller, Ross R., Gunther, Edward J.
Publicat a Cell Rep (2019)

A multistage murine breast cancer model reveals long-lived premalignant clones refractory to parity-induced protection

per Li, Shuo, Gestl, Shelley A., Gunther, Edward J.
Publicat a Cancer Prev Res (Phila) (2019)

Tumor cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers

per Cleary, Allison S., Leonard, Travis L., Gestl, Shelley A., Gunther, Edward J.
Publicat 2014

Dormant Wnt-Initiated Mammary Cancer Can Participate in Reconstituting Functional Mammary Glands

per Gestl, Shelley A., Leonard, Travis L., Biddle, Jessica L., Debies, Michael T., Gunther, Edward J.
Publicat 2007

Basal but not luminal mammary epithelial cells require PI3K/mTOR signaling for Ras-driven overgrowth

per Plichta, Kristin A., Mathers, Jessica L., Gestl, Shelley A., Glick, Adam B., Gunther, Edward J.
Publicat 2012

Carcinogen-specific mutations in preferred Ras-Raf pathway oncogenes directed by strand bias

per Keller, Ross R., Gestl, Shelley A., Lu, Amy Q., Hoke, Alicia, Feith, David J., Gunther, Edward J.
Publicat a Carcinogenesis (2016)

A BAC transgenic reporter recapitulates in vivo regulation of human telomerase reverse transcriptase in development and tumorigenesis

per Jia, Wenwen, Wang, Shuwen, Horner, James W., Wang, Ning, Wang, Huayan, Gunther, Edward J., DePinho, Ronald A., Zhu, Jiyue
Publicat 2011

Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis

per Gunther, Edward J., Moody, Susan E., Belka, George K., Hahn, Kristina T., Innocent, Nathalie, Dugan, Katherine D., Cardiff, Robert D., Chodosh, Lewis A.
Publicat 2003

Deregulated Estrogen Receptor α Expression in Mammary Epithelial Cells of Transgenic Mice Results in the Development of Ductal Carcinoma In situ

per Frech, M. Silvina, Halama, Ewa D., Tilli, Maddalena T., Singh, Baljit, Gunther, Edward J., Chodosh, Lewis A., Flaws, Jodi A., Furth, Priscilla A.
Publicat a Cancer Res (2005)

Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19(Arf)/p53 pathway lesions but not p16(Ink4a) loss

per Debies, Michael T., Gestl, Shelley A., Mathers, Jessica L., Mikse, Oliver R., Leonard, Travis L., Moody, Susan E., Chodosh, Lewis A., Cardiff, Robert D., Gunther, Edward J.
Publicat 2007

Targeting the Activator Protein 1 Transcription Factor for the Prevention of Estrogen Receptor-Negative Mammary Tumors

per Shen, Qiang, Uray, Ivan P., Li, Yuxin, Zhang, Yun, Hill, Jamal, Xu, Xiao-Chun, Young, Matthew R., Gunther, Edward J., Hilsenbeck, Susan G., Colburn, Nancy H., Chodosh, Lewis A., Brown, Powel H.
Publicat 2008

P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis

per McHenry, Peter R, Sears, James C, Herrick, Matthew P, Chang, Peggy, Heckman-Stoddard, Brandy M, Rybarczyk, Megan, Chodosh, Lewis A, Gunther, Edward J, Hilsenbeck, Susan G, Rosen, Jeffrey M, Vargo-Gogola, Tracy
Publicat 2010