Evolution of Relapse-Proficient Subclones Constrained by Collateral Sensitivity to Oncogene Overdose in Wnt-Driven Mammary Cancer

Por Keller, Ross R., Gunther, Edward J.
Publicado no Cell Rep (2019)

A multistage murine breast cancer model reveals long-lived premalignant clones refractory to parity-induced protection

Por Li, Shuo, Gestl, Shelley A., Gunther, Edward J.
Publicado no Cancer Prev Res (Phila) (2019)

Tumor cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers

Por Cleary, Allison S., Leonard, Travis L., Gestl, Shelley A., Gunther, Edward J.
Publicado em 2014

Dormant Wnt-Initiated Mammary Cancer Can Participate in Reconstituting Functional Mammary Glands

Por Gestl, Shelley A., Leonard, Travis L., Biddle, Jessica L., Debies, Michael T., Gunther, Edward J.
Publicado em 2007

Basal but not luminal mammary epithelial cells require PI3K/mTOR signaling for Ras-driven overgrowth

Por Plichta, Kristin A., Mathers, Jessica L., Gestl, Shelley A., Glick, Adam B., Gunther, Edward J.
Publicado em 2012

Carcinogen-specific mutations in preferred Ras-Raf pathway oncogenes directed by strand bias

Por Keller, Ross R., Gestl, Shelley A., Lu, Amy Q., Hoke, Alicia, Feith, David J., Gunther, Edward J.
Publicado no Carcinogenesis (2016)

A BAC transgenic reporter recapitulates in vivo regulation of human telomerase reverse transcriptase in development and tumorigenesis

Por Jia, Wenwen, Wang, Shuwen, Horner, James W., Wang, Ning, Wang, Huayan, Gunther, Edward J., DePinho, Ronald A., Zhu, Jiyue
Publicado em 2011

Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis

Por Gunther, Edward J., Moody, Susan E., Belka, George K., Hahn, Kristina T., Innocent, Nathalie, Dugan, Katherine D., Cardiff, Robert D., Chodosh, Lewis A.
Publicado em 2003

Deregulated Estrogen Receptor α Expression in Mammary Epithelial Cells of Transgenic Mice Results in the Development of Ductal Carcinoma In situ

Por Frech, M. Silvina, Halama, Ewa D., Tilli, Maddalena T., Singh, Baljit, Gunther, Edward J., Chodosh, Lewis A., Flaws, Jodi A., Furth, Priscilla A.
Publicado no Cancer Res (2005)

Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19(Arf)/p53 pathway lesions but not p16(Ink4a) loss

Por Debies, Michael T., Gestl, Shelley A., Mathers, Jessica L., Mikse, Oliver R., Leonard, Travis L., Moody, Susan E., Chodosh, Lewis A., Cardiff, Robert D., Gunther, Edward J.
Publicado em 2007

Targeting the Activator Protein 1 Transcription Factor for the Prevention of Estrogen Receptor-Negative Mammary Tumors

Por Shen, Qiang, Uray, Ivan P., Li, Yuxin, Zhang, Yun, Hill, Jamal, Xu, Xiao-Chun, Young, Matthew R., Gunther, Edward J., Hilsenbeck, Susan G., Colburn, Nancy H., Chodosh, Lewis A., Brown, Powel H.
Publicado em 2008

P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis

Por McHenry, Peter R, Sears, James C, Herrick, Matthew P, Chang, Peggy, Heckman-Stoddard, Brandy M, Rybarczyk, Megan, Chodosh, Lewis A, Gunther, Edward J, Hilsenbeck, Susan G, Rosen, Jeffrey M, Vargo-Gogola, Tracy
Publicado em 2010