Carcinogen-specific mutations in preferred Ras-Raf pathway oncogenes directed by strand bias

Carcinogen exposures inscribe mutation patterns on cancer genomes and sometimes bias the acquisition of driver mutations toward preferred oncogenes, potentially dictating sensitivity to targeted agents. Whether and how carcinogen-specific mutation patterns direct activation of preferred oncogenes re...

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Bibliographic Details
Published in:Carcinogenesis
Main Authors: Keller, Ross R., Gestl, Shelley A., Lu, Amy Q., Hoke, Alicia, Feith, David J., Gunther, Edward J.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967214/
https://ncbi.nlm.nih.gov/pubmed/27207659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgw061
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