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Carcinogen-specific mutations in preferred Ras-Raf pathway oncogenes directed by strand bias
Carcinogen exposures inscribe mutation patterns on cancer genomes and sometimes bias the acquisition of driver mutations toward preferred oncogenes, potentially dictating sensitivity to targeted agents. Whether and how carcinogen-specific mutation patterns direct activation of preferred oncogenes re...
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| Published in: | Carcinogenesis |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4967214/ https://ncbi.nlm.nih.gov/pubmed/27207659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgw061 |
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