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Carcinogen-specific mutations in preferred Ras-Raf pathway oncogenes directed by strand bias

Carcinogen exposures inscribe mutation patterns on cancer genomes and sometimes bias the acquisition of driver mutations toward preferred oncogenes, potentially dictating sensitivity to targeted agents. Whether and how carcinogen-specific mutation patterns direct activation of preferred oncogenes re...

詳細記述

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書誌詳細
出版年:Carcinogenesis
主要な著者: Keller, Ross R., Gestl, Shelley A., Lu, Amy Q., Hoke, Alicia, Feith, David J., Gunther, Edward J.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967214/
https://ncbi.nlm.nih.gov/pubmed/27207659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgw061
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