Novel Tumor Suppressor Function of Glucocorticoid-Induced TNF Receptor GITR in Multiple Myeloma

Glucocorticoid-induced TNF receptor (GITR) plays a crucial role in modulating immune response and inflammation, however the role of GITR in human cancers is poorly understood. In this study, we demonstrated that GITR is inactivated during tumor progression in Multiple Myeloma (MM) through promoter C...

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Detalhes bibliográficos
Main Authors: Liu, Yang, Quang, Phong, Braggio, Esteban, Ngo, Hai, Badalian-Very, Gayane, Flores, Ludmila, Zhang, Yong, Sacco, Antonio, Maiso, Patricia, Azab, Abdel Kareem, Azab, Feda, Carrasco, Ruben, Rollins, Barrett J., Roccaro, Aldo M., Ghobrial, Irene M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681775/
https://ncbi.nlm.nih.gov/pubmed/23785514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066982
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