Bone Marrow Mesenchymal Stromal Cells in Multiple Myeloma: Their Role as Active Contributors to Myeloma Progression

di Maiso, Patricia, Mogollón, Pedro, Ocio, Enrique M., Garayoa, Mercedes
Pubblicato in Cancers (Basel) (2021)

Biological Insights into Myeloma and Other B Cell Malignancies

di Fulciniti, Mariateresa, Amodio, Nicola, Cea, Michele, Maiso, Patricia, Azab, Abdel Kareem
Pubblicato in Biomed Res Int (2016)

Epigenetic modifications as key regulators of Waldenstrom's Macroglobulinemia biology

di Sacco, Antonio, Issa, Ghayas C, Zhang, Yong, Liu, Yang, Maiso, Patricia, Ghobrial, Irene M, Roccaro, Aldo M
Pubblicazione 2010

microRNA-dependent modulation of histone acetylation in Waldenström macroglobulinemia

di Roccaro, Aldo M., Sacco, Antonio, Jia, Xiaoying, Azab, Abdel Kareem, Maiso, Patricia, Ngo, Hai T., Azab, Feda, Runnels, Judith, Quang, Phong, Ghobrial, Irene M.
Pubblicazione 2010

The Bone Marrow Microenvironment in Waldenstrom Macroglobulinemia

di Ghobrial, Irene M., Maiso, Patricia, Azab, Abdelkareem, Liu, Yang, Zhang, Yong, Issa, Ghayas, Azab, Feda, Sacco, Antonio, Quang, Phong, Ngo, Hai, Roccaro, Aldo
Pubblicazione 2011

Metabolic signature identifies novel targets for drug resistance in Multiple Myeloma

di Maiso, Patricia, Huynh, Daisy, Moschetta, Michele, Sacco, Antonio, Aljawai, Yosra, Mishima, Yuji, Asara, John M., Roccaro, Aldo M., Kimmelman, Alec C., Ghobrial, Irene M.
Pubblicato in Cancer Res (2015)

Targeting the bone marrow in Waldenstrom Macroglobulinemia

di Ghobrial, Irene M., Zhang, Yong, Liu, Yang, Ngo, Hai, Azab, Feda, Sacco, Antonio, Azab, Abdelkareem, Maiso, Patricia, Morgan, Brittany, Quang, Phong, Issa, Ghayas, Leleu, Xavier, Roccaro, Aldo
Pubblicazione 2011

Selective inhibition of chymotrypsin-like activity of the immunoproteasome and constitutive proteasome in Waldenström macroglobulinemia

di Roccaro, Aldo M., Sacco, Antonio, Aujay, Monette, Ngo, Hai T., Azab, Abdel Kareem, Azab, Feda, Quang, Phong, Maiso, Patricia, Runnels, Judith, Anderson, Kenneth C., Demo, Susan, Ghobrial, Irene M.
Pubblicazione 2010

BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression

di Roccaro, Aldo M., Sacco, Antonio, Maiso, Patricia, Azab, Abdel Kareem, Tai, Yu-Tzu, Reagan, Michaela, Azab, Feda, Flores, Ludmila M., Campigotto, Federico, Weller, Edie, Anderson, Kenneth C., Scadden, David T., Ghobrial, Irene M.
Pubblicazione 2013

BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression

di Roccaro, Aldo M., Sacco, Antonio, Maiso, Patricia, Azab, Abdel Kareem, Tai, Yu-Tzu, Reagan, Michaela, Azab, Feda, Flores, Ludmila M., Campigotto, Federico, Weller, Edie, Anderson, Kenneth C., Scadden, David T., Ghobrial, Irene M.
Pubblicazione 2013

Novel Tumor Suppressor Function of Glucocorticoid-Induced TNF Receptor GITR in Multiple Myeloma

di Liu, Yang, Quang, Phong, Braggio, Esteban, Ngo, Hai, Badalian-Very, Gayane, Flores, Ludmila, Zhang, Yong, Sacco, Antonio, Maiso, Patricia, Azab, Abdel Kareem, Azab, Feda, Carrasco, Ruben, Rollins, Barrett J., Roccaro, Aldo M., Ghobrial, Irene M.
Pubblicazione 2013

In vitro and in vivo rationale for the triple combination of panobinostat (LBH589) and dexamethasone with either bortezomib or lenalidomide in multiple myeloma

di Ocio, Enrique M., Vilanova, David, Atadja, Peter, Maiso, Patricia, Crusoe, Edvan, Fernández-Lázaro, Diego, Garayoa, Mercedes, San-Segundo, Laura, Hernández-Iglesias, Teresa, de Álava, Enrique, Shao, Wenlin, Yao, Yung-Mae, Pandiella, Atanasio, San-Miguel, Jesús F.
Pubblicazione 2010

Characterization of freshly isolated bone marrow mesenchymal stromal cells from healthy donors and patients with multiple myeloma: transcriptional modulation of the microenvironmen...

di Alameda, Daniel, Saez, Borja, Lara-Astiaso, David, Sarvide, Sarai, Lasa, Marta, Alignani, Diego, Rodriguez, Idoia, Garate, Sonia, Vilas, Amaia, Paiva, Bruno, Alfonso-Olmos, Matias, de Espinosa, Jose Maria Lamo, Prosper, Felipe, Miguel, Jesus F. San, Maiso, Patricia
Pubblicato in Haematologica (2020)

Dual targeting of the PI3K/Akt/mTOR pathway as an antitumor strategy in Waldenstrom macroglobulinemia

di Roccaro, Aldo M., Sacco, Antonio, Husu, Emanuel N., Pitsillides, Costas, Vesole, Steven, Azab, Abdel Kareem, Azab, Feda, Melhem, Molly, Ngo, Hai T., Quang, Phong, Maiso, Patricia, Runnels, Judith, Liang, Mei-Chih, Wong, Kwok-Kin, Lin, Charles, Ghobrial, Irene M.
Pubblicazione 2010

Defining the role of TORC1/2 in multiple myeloma

di Maiso, Patricia, Liu, Yi, Morgan, Brittany, Azab, Abdel Kareem, Ren, Pingda, Martin, Michel B., Zhang, Yong, Liu, Yang, Sacco, Antonio, Ngo, Hai, Azab, Feda, Quang, Phong, Rodig, Scott J., Lin, Charles P., Roccaro, Aldo M., Rommel, Christian, Ghobrial, Irene M.
Pubblicazione 2011

CD69 is a direct HIF-1α target gene in hypoxia as a mechanism enhancing expression on tumor-infiltrating T lymphocytes

di Labiano, Sara, Meléndez-Rodríguez, Florinda, Palazón, Asís, Teijeira, Álvaro, Garasa, Saray, Etxeberria, Iñaki, Aznar, M. Ángela, Sánchez-Paulete, Alfonso R., Azpilikueta, Arantza, Bolaños, Elixabet, Molina, Carmen, de la Fuente, Hortensia, Maiso, Patricia, Sánchez-Madrid, Francisco, de Landázuri, Manuel Ortiz, Aragonés, Julián, Melero, Ignacio
Pubblicato in Oncoimmunology (2017)

P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment

di Azab, Abdel Kareem, Quang, Phong, Azab, Feda, Pitsillides, Costas, Thompson, Brian, Chonghaile, Triona, Patton, John T., Maiso, Patricia, Monrose, Val, Sacco, Antonio, Ngo, Hai T., Flores, Ludmila M., Lin, Charles P., Magnani, John L., Kung, Andrew L., Letai, Anthony, Carrasco, Ruben, Roccaro, Aldo M., Ghobrial, Irene M.
Pubblicazione 2012

Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features

di Azab, Abdel Kareem, Hu, Jinsong, Quang, Phong, Azab, Feda, Pitsillides, Costas, Awwad, Rana, Thompson, Brian, Maiso, Patricia, Sun, Jessica D., Hart, Charles P., Roccaro, Aldo M., Sacco, Antonio, Ngo, Hai T., Lin, Charles P., Kung, Andrew L., Carrasco, Ruben D., Vanderkerken, Karin, Ghobrial, Irene M.
Pubblicazione 2012

Zalypsis has in vitro activity in acute myeloid blasts and leukemic progenitor cells through the induction of a DNA damage response

di Colado, Enrique, Paíno, Teresa, Maiso, Patricia, Ocio, Enrique M., Chen, Xi, Álvarez-Fernández, Stela, Gutiérrez, Norma C., Martín-Sánchez, Jesús, Flores-Montero, Juan, San Segundo, Laura, Garayoa, Mercedes, Fernández-Lázaro, Diego, Vidriales, Maria-Belen, Galmarini, Carlos M., Avilés, Pablo, Cuevas, Carmen, Pandiella, Atanasio, San-Miguel, Jesús F.
Pubblicazione 2011

SDF-1 inhibition targets the bone marrow niche for cancer therapy

di Roccaro, Aldo M., Sacco, Antonio, Purschke, Werner G., Moschetta, Michele, Buchner, Klaus, Maasch, Christian, Zboralski, Dirk, Zöllner, Stefan, Vonhoff, Stefan, Mishima, Yuji, Maiso, Patricia, Reagan, Michaela R., Lonardi, Silvia, Ungari, Marco, Facchetti, Fabio, Eulberg, Dirk, Kruschinski, Anna, Vater, Axel, Rossi, Giuseppe, Klussmann, Sven, Ghobrial, Irene M.
Pubblicazione 2014