Defining the role of TORC1/2 in multiple myeloma

Mammalian target of rapamycin (mTOR) is a downstream serine/threonine kinase of the PI3K/Akt pathway that integrates signals from the tumor microenvironment to regulate multiple cellular processes. Rapamycin and its analogs have not shown significant activity in multiple myeloma (MM), likely because...

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Dades bibliogràfiques
Autors principals: Maiso, Patricia, Liu, Yi, Morgan, Brittany, Azab, Abdel Kareem, Ren, Pingda, Martin, Michel B., Zhang, Yong, Liu, Yang, Sacco, Antonio, Ngo, Hai, Azab, Feda, Quang, Phong, Rodig, Scott J., Lin, Charles P., Roccaro, Aldo M., Rommel, Christian, Ghobrial, Irene M.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2011
Matèries:
Lymphoid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245208/
https://ncbi.nlm.nih.gov/pubmed/22045983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-342394
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