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Intrinsic Noise Profoundly Alters the Dynamics and Steady State of Morphogen-Controlled Bistable Genetic Switches

During tissue development, patterns of gene expression determine the spatial arrangement of cell types. In many cases, gradients of secreted signalling molecules—morphogens—guide this process by controlling downstream transcriptional networks. A mechanism commonly used in these networks to convert t...

詳細記述

保存先:
書誌詳細
出版年:PLoS Comput Biol
主要な著者: Perez-Carrasco, Ruben, Guerrero, Pilar, Briscoe, James, Page, Karen M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074595/
https://ncbi.nlm.nih.gov/pubmed/27768683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005154
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