The role of polycomb repressive complex 2 in early T-cell precursor acute lymphoblastic leukemia

Por Bernt, Kathrin M., Neff, Tobias
Publicado no Mol Cell Oncol (2018)

Current Concepts in Pediatric Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Por Bernt, Kathrin M., Hunger, Stephen P.
Publicado em 2014

Leukemia Stem Cells and Human Acute Lymphoblastic Leukemia

Por Bernt, Kathrin M., Armstrong, Scott A.
Publicado em 2009

MLL-Rearranged Leukemias—An Update on Science and Clinical Approaches

Por Winters, Amanda C., Bernt, Kathrin M.
Publicado no Front Pediatr (2017)

The Functional Role of PRC2 in Early T-cell Precursor Acute Lymphoblastic Leukemia (ETP-ALL) – Mechanisms and Opportunities

Por Bernt, Kathrin M., Hunger, Stephen P., Neff, Tobias
Publicado no Front Pediatr (2016)

Transient Potential Receptor Melastatin-2 (TRPM2) Does Not Influence Murine MLL-AF9 Driven AML Leukemogenesis or in Vitro Response to Chemotherapy

Por Haladyna, Jessica N., Pastuer, Taylor, Riedel, Simone S, Perraud, Anne-Laure, Bernt, Kathrin M
Publicado no Exp Hematol (2016)

DOT1L-Mediated H3K79 Methylation in Chromatin Is Dispensable for Wnt Pathway-Specific and Other Intestinal Epithelial Functions

Por Ho, Li-Lun, Sinha, Amit, Verzi, Michael, Bernt, Kathrin M., Armstrong, Scott A., Shivdasani, Ramesh A.
Publicado em 2013

Inactivation of Eed Impedes MLL-AF9 Mediated Leukemogenesis Through Cdkn2a-Dependent and Cdkn2a-Independent Mechanisms in a Murine Model

Por Danis, Etienne, Yamauchi, Taylor, Echanique, Kristen, Haladyna, Jessica, Kalkur, Roshni, Riedel, Simone, Zhu, Nan, Xie, Huafeng, Bernt, Kathrin M., Orkin, Stuart H., Armstrong, Scott A., Neff, Tobias
Publicado no Exp Hematol (2015)

Abrogation of MLL-AF10 and CALM-AF10 mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l

Por Chen, Liying, Deshpande, Aniruddha, Banka, Deepti, Bernt, Kathrin M., Dias, Stuart, Buske, Christian, Olhava, Edward J., Daigle, Scott R., Richon, Victoria M., Pollock, Roy M., Armstrong, Scott A.
Publicado em 2012

Ezh2 Controls an Early Hematopoietic Program and Growth and Survival Signaling in Early T Cell Precursor Acute Lymphoblastic Leukemia

Por Danis, Etienne, Yamauchi, Taylor, Echanique, Kristen, Zhang, Xi, Haladyna, Jessica N., Riedel, Simone S., Zhu, Nan, Xie, Huafeng, Orkin, Stuart H., Armstrong, Scott A., Bernt, Kathrin M., Neff, Tobias
Publicado no Cell Rep (2016)

Chromatin modifying enzymes as modulators of reprogramming

Por Onder, Tamer T., Kara, Nergis, Cherry, Anne, Sinha, Amit U., Zhu, Nan, Bernt, Kathrin M., Cahan, Patrick, Mancarci, Ogan. B., Unternaehrer, Juli, Gupta, Piyush B., Lander, Eric S., Armstrong, Scott A., Daley, George Q.
Publicado em 2012

Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l

Por Deshpande, Aniruddha J., Chen, Liying, Fazio, Maurizio, Sinha, Amit U., Bernt, Kathrin M., Banka, Deepti, Dias, Stuart, Chang, Jenny, Olhava, Edward J., Daigle, Scott R., Richon, Victoria M., Pollock, Roy M., Armstrong, Scott A.
Publicado em 2013

MLL-rearranged Leukemia is Dependent on Aberrant H3K79 Methylation by DOT1L

Por Bernt, Kathrin M., Zhu, Nan, Sinha, Amit U., Vempati, Sridhar, Faber, Joerg, Krivtsov, Andrei V., Feng, Zhaohui, Punt, Natalie, Daigle, Amanda, Bullinger, Lars, Pollock, Roy M., Richon, Victoria M., Kung, Andrew L., Armstrong, Scott A.
Publicado em 2011

MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia

Por Riedel, Simone S., Haladyna, Jessica N., Bezzant, Matthew, Stevens, Brett, Pollyea, Daniel A., Sinha, Amit U., Armstrong, Scott A., Wei, Qi, Pollock, Roy M., Daigle, Scott R., Jordan, Craig T., Ernst, Patricia, Neff, Tobias, Bernt, Kathrin M.
Publicado no J Clin Invest (2016)

AF10 Regulates Progressive H3K79 Methylation and HOX Gene Expression in Diverse AML Subtypes

Por Deshpande, Aniruddha J., Deshpande, Anagha, Sinha, Amit U., Chen, Liying, Chang, Jenny, Cihan, Ali, Fazio, Maurizio, Chen, Chun-wei, Zhu, Nan, Koche, Richard, Dzhekieva, Liuda, Ibáñez, Gloria, Dias, Stuart, Banka, Deepti, Krivtsov, Andrei, Luo, Minkui, Roeder, Robert G., Bradner, James E., Bernt, Kathrin M., Armstrong, Scott A.
Publicado no Cancer Cell (2014)

Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor

Por Daigle, Scott R., Olhava, Edward J., Therkelsen, Carly A., Majer, Christina R., Sneeringer, Christopher J., Song, Jeffrey, Johnston, L. Danielle, Scott, Margaret Porter, Smith, Jesse J., Xiao, Yonghong, Jin, Lei, Kuntz, Kevin W., Chesworth, Richard, Moyer, Mikel P., Bernt, Kathrin M., Tseng, Jen-Chieh, Kung, Andrew L., Armstrong, Scott A., Copeland, Robert A., Richon, Victoria M., Pollock, Roy M.
Publicado em 2011