Computational Tools for Stem Cell Biology

Por Bian, Qin, Cahan, Patrick
Publicado no Trends Biotechnol (2016)

Integrated genomics of susceptibility to alkylator-induced leukemia in mice

Por Cahan, Patrick, Graubert, Timothy A
Publicado em 2010

Origins and implications of pluripotent stem cell variability and heterogeneity

Por Cahan, Patrick, Daley, George Q.
Publicado em 2013

Understanding development and stem cells using single cell-based analyses of gene expression

Por Kumar, Pavithra, Tan, Yuqi, Cahan, Patrick
Publicado no Development (2017)

The impact of copy number variation on local gene expression in mouse hematopoietic stem/progenitor cells

Por Cahan, Patrick, Li, Yedda, Izumi, Masayo, Graubert, Timothy A.
Publicado em 2009

Defining cellular identity through network biology

Por Cahan, Patrick, Morris, Samantha A, Collins, James J, Daley, George Q
Publicado no Cell Cycle (2014)

Meta-Analysis of Microarray Results: Challenges, Opportunities, and Recommendations for Standardization

Por Cahan, Patrick, Rovegno, Felicia, Mooney, Denise, Newman, John C., Laurent, Georges St., McCaffrey, Timothy A.
Publicado em 2007

POU4F1 is associated with t(8;21) acute myeloid leukemia and contributes directly to its unique transcriptional signature

Por Fortier, Julie M., Payton, Jacqueline E., Cahan, Patrick, Ley, Timothy J., Walter, Matthew J., Graubert, Timothy A.
Publicado em 2010

CellNet: Network Biology Applied to Stem Cell Engineering

Por Cahan, Patrick, Li, Hu, Morris, Samantha A., da Rocha, Edroaldo Lummertz, Daley, George Q., Collins, James J.
Publicado no Cell (2014)

Structural Variation of the Mouse Natural Killer Gene Complex

Por Higuchi, Darryl A., Cahan, Patrick, Gao, Jian, Ferris, Stephen T., Poursine-Laurent, Jennifer, Graubert, Timothy A., Yokoyama, Wayne M.
Publicado em 2010

Transcriptional Landscape of Cardiomyocyte Maturation

Por Uosaki, Hideki, Cahan, Patrick, Lee, Dong I., Wang, Songnan, Miyamoto, Matthew, Fernandez, Laviel, Kass, David A., Kwon, Chulan
Publicado no Cell Rep (2015)

Poly(A)-specific ribonuclease (PARN) mediates 3′-end maturation of the telomerase RNA component

Por Moon, Diane H, Segal, Matthew, Boyraz, Baris, Guinan, Eva, Hofmann, Inga, Cahan, Patrick, Tai, Albert K, Agarwal, Suneet
Publicado no Nat Genet (2015)

Posttranscriptional manipulation of TERC reverses molecular hallmarks of telomere disease

Por Boyraz, Baris, Moon, Diane H., Segal, Matthew, Muosieyiri, Maud Z., Aykanat, Asli, Tai, Albert K., Cahan, Patrick, Agarwal, Suneet
Publicado no J Clin Invest (2016)

Dissecting engineered cell types and enhancing cell fate conversion via CellNet

Por Morris, Samantha A., Cahan, Patrick, Li, Hu, Zhao, Anna M., San Roman, Adrianna K., Shivdasani, Ramesh A., Collins, James J., Daley, George Q.
Publicado no Cell (2014)

Hippo Pathway Activity Influences Liver Cell Fate

Por Yimlamai, Dean, Christodoulou, Constantina, Galli, Giorgio G., Yanger, Kilangsungla, Pepe-Mooney, Brian, Gurung, Basanta, Shrestha, Kriti, Cahan, Patrick, Stanger, Ben Z., Camargo, Fernando D.
Publicado em 2014

A nontranscriptional role for Oct4 in the regulation of mitotic entry

Por Zhao, Rui, Deibler, Richard W., Lerou, Paul H., Ballabeni, Andrea, Heffner, Garrett C., Cahan, Patrick, Unternaehrer, Juli J., Kirschner, Marc W., Daley, George Q.
Publicado no Proc Natl Acad Sci U S A (2014)

wuHMM: a robust algorithm to detect DNA copy number variation using long oligonucleotide microarray data

Por Cahan, Patrick, Godfrey, Laura E., Eis, Peggy S., Richmond, Todd A., Selzer, Rebecca R., Brent, Michael, McLeod, Howard L., Ley, Timothy J., Graubert, Timothy A.
Publicado em 2008

Involvement of HTLV-I Tax and CREB in aneuploidy: a bioinformatics approach

Por de la Fuente, Cynthia, Gupta, Madhur V, Klase, Zachary, Strouss, Katharine, Cahan, Patrick, McCaffery, Timothy, Galante, Anthony, Soteropoulos, Patricia, Pumfery, Anne, Fujii, Masahiro, Kashanchi, Fatah
Publicado em 2006

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity

Por Lu, Yi-Fen, Cahan, Patrick, Ross, Samantha, Sahalie, Julie, Sousa, Patricia M., Hadland, Brandon K., Cai, Wenqing, Serrao, Erik, Engelman, Alan N., Bernstein, Irwin D., Daley, George Q.
Publicado no Cell Rep (2016)

A High-Resolution Map of Segmental DNA Copy Number Variation in the Mouse Genome

Por Graubert, Timothy A, Cahan, Patrick, Edwin, Deepa, Selzer, Rebecca R, Richmond, Todd A, Eis, Peggy S, Shannon, William D, Li, Xia, McLeod, Howard L, Cheverud, James M, Ley, Timothy J
Publicado em 2007