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Integrated genomics of susceptibility to alkylator-induced leukemia in mice

BACKGROUND: Therapy-related acute myeloid leukemia (t-AML) is a secondary, generally incurable, malignancy attributable to chemotherapy exposure. Although there is a genetic component to t-AML susceptibility in mice, the relevant loci and the mechanism(s) by which they contribute to t-AML are largel...

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Detalhes bibliográficos
Main Authors: Cahan, Patrick, Graubert, Timothy A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018144/
https://ncbi.nlm.nih.gov/pubmed/21080971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-638
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