Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice

Apoptosis and the DNA damage responses have been implicated in hematopoietic development and differentiation, as well as in the pathogenesis of myelodysplastic syndromes (MDS) and leukemia. However, the importance of late-stage mediators of apoptosis in hematopoiesis and leukemogenesis has not been...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Lu, Elise Peterson, McLellan, Michael, Ding, Li, Fulton, Robert, Mardis, Elaine R., Wilson, Richard K., Miller, Christopher A., Westervelt, Peter, DiPersio, John F., Link, Daniel C., Walter, Matthew J., Ley, Timothy J., Graubert, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271179/
https://ncbi.nlm.nih.gov/pubmed/25349173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-582551
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