Clonal diversity of recurrently mutated genes in myelodysplastic syndromes

Recent studies suggest that most cases of myelodysplastic syndrome (MDS) are clonally heterogeneous, with a founding clone and multiple subclones. It is not known whether specific gene mutations typically occur in founding clones or subclones. We screened a panel of 94 candidate genes in a cohort of...

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Detalhes bibliográficos
Main Authors: Walter, MJ, Shen, D, Shao, J, Ding, L, White, BS, Kandoth, C, Miller, CA, Niu, B, McLellan, MD, Dees, ND, Fulton, R, Elliot, K, Heath, S, Grillot, M, Westervelt, P, Link, DC, DiPersio, JF, Mardis, E, Ley, TJ, Wilson, RK, Graubert, TA
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736571/
https://ncbi.nlm.nih.gov/pubmed/23443460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.58
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