Clonal Architecture of Secondary Acute Myeloid Leukemia Defined by Single-Cell Sequencing

Next-generation sequencing has been used to infer the clonality of heterogeneous tumor samples. These analyses yield specific predictions—the population frequency of individual clones, their genetic composition, and their evolutionary relationships—which we set out to test by sequencing individual c...

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Detalhes bibliográficos
Main Authors: Hughes, Andrew E. O., Magrini, Vincent, Demeter, Ryan, Miller, Christopher A., Fulton, Robert, Fulton, Lucinda L., Eades, William C., Elliott, Kevin, Heath, Sharon, Westervelt, Peter, Ding, Li, Conrad, Donald F., White, Brian S., Shao, Jin, Link, Daniel C., DiPersio, John F., Mardis, Elaine R., Wilson, Richard K., Ley, Timothy J., Walter, Matthew J., Graubert, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091781/
https://ncbi.nlm.nih.gov/pubmed/25010716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004462
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