Subclones dominate at MDS progression following allogeneic hematopoietic cell transplant

Allogeneic hematopoietic cell transplantation (alloHCT) is a potentially curative treatment for myelodysplastic syndromes (MDS), but patients who relapse after transplant have poor outcomes. In order to understand the contribution of tumor clonal evolution to disease progression,we applied exome and...

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發表在:JCI Insight
Main Authors: Jacoby, Meagan A., Duncavage, Eric J., Chang, Gue Su, Miller, Christopher A., Shao, Jin, Elliott, Kevin, Robinson, Joshua, Fulton, Robert S., Fronick, Catrina C., O’Laughlin, Michelle, Heath, Sharon E., Pusic, Iskra, Welch, John S., Link, Daniel C., DiPersio, John F., Westervelt, Peter, Ley, Timothy J., Graubert, Timothy A., Walter, Matthew J.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2018
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922277/
https://ncbi.nlm.nih.gov/pubmed/29515031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98962
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