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Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia

Familial clustering of myelodysplastic syndromes (MDSs) and acute myeloid leukemia (AML) can be caused by inherited factors. We screened 59 individuals from 17 families with 2 or more biological relatives with MDS/AML for variants in 12 genes with established roles in predisposition to MDS/AML, and...

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Pubblicato in:Blood
Autori principali: Churpek, Jane E., Pyrtel, Khateriaa, Kanchi, Krishna-Latha, Shao, Jin, Koboldt, Daniel, Miller, Christopher A., Shen, Dong, Fulton, Robert, O’Laughlin, Michelle, Fronick, Catrina, Pusic, Iskra, Uy, Geoffrey L., Braunstein, Evan M., Levis, Mark, Ross, Julie, Elliott, Kevin, Heath, Sharon, Jiang, Allan, Westervelt, Peter, DiPersio, John F., Link, Daniel C., Walter, Matthew J., Welch, John, Wilson, Richard, Ley, Timothy J., Godley, Lucy A., Graubert, Timothy A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661171/
https://ncbi.nlm.nih.gov/pubmed/26492932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-04-641100
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