Dynamic Changes in the Clonal Structure of MDS and AML in Response to Epigenetic Therapy

Traditional response criteria in MDS and AML are based on bone marrow morphology and may not accurately reflect clonal tumor burden in patients treated with non-cytotoxic chemotherapy. We used next-generation sequencing of serial bone marrow samples to monitor MDS and AML tumor burden during treatme...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Leukemia
Egile Nagusiak: Uy, Geoffrey L., Duncavage, Eric J., Chang, Gue Su, Jacoby, Meagan A., Miller, Christopher A., Shao, Jin, Heath, Sharon, Elliott, Kevin, Reinick, Teresa, Fulton, Robert S., Fronick, Catrina C., O’Laughlin, Michelle, Ganel, Liron, Abboud, Camille N., Cashen, Amanda F., DiPersio, John F., Wilson, Richard K, Link, Daniel C., Welch, John S., Ley, Timothy J., Graubert, Timothy A., Westervelt, Peter, Walter, Matthew J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382101/
https://ncbi.nlm.nih.gov/pubmed/27740633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.282
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