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Immune Escape of Relapsed AML Cells after Allogeneic Transplantation

BACKGROUND: As consolidation therapy for acute myeloid leukemia (AML), allogeneic hematopoietic stem-cell transplantation provides a benefit in part by means of an immune-mediated graft-versus-leukemia effect. We hypothesized that the immune-mediated selective pressure imposed by allogeneic transpla...

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Detalhes bibliográficos
Publicado no:N Engl J Med
Main Authors: Christopher, Matthew J., Petti, Allegra A., Rettig, Michael P., Miller, Christopher A., Chendamarai, Ezhilarasi, Duncavage, Eric J., Klco, Jeffery M., Helton, Nicole M., O’Laughlin, Michelle, Fronick, Catrina C., Fulton, Robert S., Wilson, Richard K., Wartman, Lukas D., Welch, John S., Heath, Sharon E., Baty, Jack D., Payton, Jacqueline E., Graubert, Timothy A., Link, Daniel C., Walter, Matthew J., Westervelt, Peter, Ley, Timothy J., DiPersio, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322675/
https://ncbi.nlm.nih.gov/pubmed/30380364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1808777
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