Hippo Pathway Activity Influences Liver Cell Fate

por Yimlamai, Dean, Christodoulou, Constantina, Galli, Giorgio G., Yanger, Kilangsungla, Pepe-Mooney, Brian, Gurung, Basanta, Shrestha, Kriti, Cahan, Patrick, Stanger, Ben Z., Camargo, Fernando D.
Publicado em 2014

p190 RhoGAP promotes contact inhibition in epithelial cells by repressing YAP activity

por Frank, Scott R., Köllmann, Clemens P., Luong, Phi, Galli, Giorgio G., Zou, Lihua, Bernards, André, Getz, Gad, Calogero, Raffaele A., Frödin, Morten, Hansen, Steen H.
Publicado no J Cell Biol (2018)

Correction: p190 RhoGAP promotes contact inhibition in epithelial cells by repressing YAP activity

por Frank, Scott R., Köllmann, Clemens P., Luong, Phi, Galli, Giorgio G., Zou, Lihua, Bernards, André, Getz, Gad, Calogero, Raffaele A., Frödin, Morten, Hansen, Steen H.
Publicado no J Cell Biol (2018)

NUAK2 is a critical YAP target in liver cancer

por Yuan, Wei-Chien, Pepe-Mooney, Brian, Galli, Giorgio G., Dill, Michael T., Huang, Hai-Tsang, Hao, Mingfeng, Wang, Yumeng, Liang, Han, Calogero, Raffaele A., Camargo, Fernando D.
Publicado no Nat Commun (2018)

A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation

por Korkmaz, Gozde, Manber, Zohar, Lopes, Rui, Prekovic, Stefan, Schuurman, Karianne, Kim, Yongsoo, Teunissen, Hans, Flach, Koen, de Wit, Elzo, Galli, Giorgio G, Zwart, Wilbert, Elkon, Ran, Agami, Reuven
Publicado no Nucleic Acids Res (2019)

YAP drives growth by controlling transcriptional pause release from dynamic enhancers

por Galli, Giorgio G., Carrara, Matteo, Yuan, Wei-Chien, Valdes-Quezada, Christian, Gurung, Basanta, Pepe-Mooney, Brian, Zhang, Tinghu, Geeven, Geert, Gray, Nathanael S, de Laat, Wouter, Calogero, Raffaele A., Camargo, Fernando D.
Publicado no Mol Cell (2015)

A role for repressive complexes and H3K9 di-methylation in PRDM5-associated brittle cornea syndrome

por Porter, Louise F., Galli, Giorgio G., Williamson, Sally, Selley, Julian, Knight, David, Elcioglu, Nursel, Aydin, Ali, Elcioglu, Mustafa, Venselaar, Hanka, Lund, Anders H., Bonshek, Richard, Black, Graeme C., Manson, Forbes D.
Publicado no Hum Mol Genet (2015)

Therapeutic Assessment of Targeting ASNS Combined with l-Asparaginase Treatment in Solid Tumors and Investigation of Resistance Mechanisms

por Apfel, Verena, Begue, Damien, Cordo’, Valentina, Holzer, Laura, Martinuzzi, Laetitia, Buhles, Alexandra, Kerr, Grainne, Barbosa, Ines, Naumann, Ulrike, Piquet, Michelle, Ruddy, David, Weiss, Andreas, Ferretti, Stephane, Almeida, Reinaldo, Bonenfant, Debora, Tordella, Luca, Galli, Giorgio G.
Publicado no ACS Pharmacol Transl Sci (2021)

Identification of the HECT E3 ligase UBR5 as a regulator of MYC degradation using a CRISPR/Cas9 screen

por Schukur, Lina, Zimmermann, Tamara, Niewoehner, Ole, Kerr, Grainne, Gleim, Scott, Bauer-Probst, Beatrice, Knapp, Britta, Galli, Giorgio G., Liang, Xiaoyou, Mendiola, Angelica, Reece-Hoyes, John, Rapti, Melivoia, Barbosa, Ines, Reschke, Markus, Radimerski, Thomas, Thoma, Claudio R.
Publicado no Sci Rep (2020)

PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma

por Bleu, Melusine, Gaulis, Swann, Lopes, Rui, Sprouffske, Kathleen, Apfel, Verena, Holwerda, Sjoerd, Pregnolato, Marco, Yildiz, Umut, Cordoʹ, Valentina, Dost, Antonella F. M., Knehr, Judith, Carbone, Walter, Lohmann, Felix, Lin, Charles Y., Bradner, James E., Kauffmann, Audrey, Tordella, Luca, Roma, Guglielmo, Galli, Giorgio G.
Publicado no Nat Commun (2019)

Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth

por Cox, Andrew G., Hwang, Katie L., Brown, Kristin K., Evason, Kimberley, Beltz, Sebastian, Tsomides, Allison, O'Connor, Keelin, Galli, Giorgio G., Yimlamai, Dean, Chhangawala, Sagar, Yuan, Min, Lien, Evan C., Wucherpfennig, Julia, Nissim, Sahar, Minami, Akihiro, Cohen, David E., Camargo, Fernando D., Asara, John M., Houvras, Yariv, Stainier, Didier Y.R., Goessling, Wolfram
Publicado no Nat Cell Biol (2016)

Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth

por Cox, Andrew G, Tsomides, Allison, Yimlamai, Dean, Hwang, Katie L, Miesfeld, Joel, Galli, Giorgio G, Fowl, Brendan H, Fort, Michael, Ma, Kimberly Y, Sullivan, Mark R, Hosios, Aaron M, Snay, Erin, Yuan, Min, Brown, Kristin K, Lien, Evan C, Chhangawala, Sagar, Steinhauser, Matthew L, Asara, John M, Houvras, Yariv, Link, Brian, Vander Heiden, Matthew G, Camargo, Fernando D, Goessling, Wolfram
Publicado no EMBO J (2018)

The Landscape of Cancer Cell Line Metabolism

por Li, Haoxin, Ning, Shaoyang, Ghandi, Mahmoud, Kryukov, Gregory V., Gopal, Shuba, Deik, Amy, Souza, Amanda, Pierce, Kerry, Keskula, Paula, Hernandez, Desiree, Ann, Julie, Shkoza, Dojna, Apfel, Verena, Zou, Yilong, Vazquez, Francisca, Barretina, Jordi, Pagliarini, Raymond A., Galli, Giorgio G., Root, David E., Hahn, William C., Tsherniak, Aviad, Giannakis, Marios, Schreiber, Stuart L., Clish, Clary B., Garraway, Levi A., Sellers, William R.
Publicado no Nat Med (2019)

PAX8 lineage-driven T cell engaging antibody for the treatment of high-grade serous ovarian cancer

por Lee, Emily, Szvetecz, Sarah, Polli, Ryan, Grauel, Angelo, Chen, Jayson, Judge, Joyce, Jaiswal, Smita, Maeda, Rie, Schwartz, Stephanie, Voedisch, Bernd, Piksa, Mateusz, Japutra, Chietara, Sadhasivam, Lingheswar, Wang, Yiqin, Carrion, Ana, Isim, Sinan, Liang, Jinsheng, Nicholson, Thomas, Lei, Hong, Fang, Qing, Steinkrauss, Michelle, Walker, Dana, Wagner, Joel, Cremasco, Viviana, Wang, Hui Qin, Galli, Giorgio G., Granda, Brian, Mansfield, Keith, Simmons, Quincey, Nguyen, Andrew Anh, Vincent Jordan, Nicole
Publicado no Sci Rep (2021)