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A nontranscriptional role for Oct4 in the regulation of mitotic entry

Rapid progression through the cell cycle and a very short G1 phase are defining characteristics of embryonic stem cells. This distinct cell cycle is driven by a positive feedback loop involving Rb inactivation and reduced oscillations of cyclins and cyclin-dependent kinase (Cdk) activity. In this se...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhao, Rui, Deibler, Richard W., Lerou, Paul H., Ballabeni, Andrea, Heffner, Garrett C., Cahan, Patrick, Unternaehrer, Juli J., Kirschner, Marc W., Daley, George Q.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226071/
https://ncbi.nlm.nih.gov/pubmed/25324523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417518111
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