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Cell cycle adaptations of embryonic stem cells
ES cells proliferate with very short gap phases yet maintain their capacity to differentiate. It had been thought that the levels of cyclins and other substrates of ubiquitin ligase APC/C remain nearly constant and Cdk activity remains constitutively high in mouse ES cells. Here we demonstrate that...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3228440/ https://ncbi.nlm.nih.gov/pubmed/22084091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116794108 |
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