Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity

Hematopoietic stem cell (HSC) transplantation is curative for malignant and genetic blood disorders, but is limited by donor availability and immune-mismatch. Deriving HSCs from patient-matched embryonic/induced-pluripotent stem cells (ESC/iPSCs) could address these limitations. Prior efforts in mur...

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Vydáno v:Cell Rep
Hlavní autoři: Lu, Yi-Fen, Cahan, Patrick, Ross, Samantha, Sahalie, Julie, Sousa, Patricia M., Hadland, Brandon K., Cai, Wenqing, Serrao, Erik, Engelman, Alan N., Bernstein, Irwin D., Daley, George Q.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247798/
https://ncbi.nlm.nih.gov/pubmed/28009288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.077
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