Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging

A hallmark of adult hematopoiesis is the continuous replacement of blood cells with limited lifespans. While active hematopoietic stem cell (HSC) contribution to multilineage hematopoiesis is the foundation of clinical HSC transplantation, recent reports have questioned the physiological contributio...

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Foilsithe in:eLife
Main Authors: Säwen, Petter, Eldeeb, Mohamed, Erlandsson, Eva, Kristiansen, Trine A, Laterza, Cecilia, Kokaia, Zaal, Karlsson, Göran, Yuan, Joan, Soneji, Shamit, Mandal, Pankaj K, Rossi, Derrick J, Bryder, David
Formáid: Artigo
Teanga:Inglês
Foilsithe: eLife Sciences Publications, Ltd 2018
Ábhair:
Stem Cells and Regenerative Medicine
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298771/
https://ncbi.nlm.nih.gov/pubmed/30561324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41258
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