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Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis

Homeostasis of short-lived blood cells is dependent on rapid proliferation of immature precursors. Using a conditional histone 2B-mCherry-labeling mouse model, we characterize hematopoietic stem cell (HSC) and progenitor proliferation dynamics in steady state and following several types of induced s...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Säwén, Petter, Lang, Stefan, Mandal, Pankaj, Rossi, Derrick J., Soneji, Shamit, Bryder, David
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819906/
https://ncbi.nlm.nih.gov/pubmed/26997272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.073
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