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Continuous mitotic activity of primitive hematopoietic stem cells in adult mice

The proliferative activity of aging hematopoietic stem cells (HSCs) is controversially discussed. Inducible fluorescent histone 2B fusion protein (H2B-FP) transgenic mice are important tools for tracking the mitotic history of murine HSCs in label dilution experiments. A recent study proposed that p...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Morcos, Mina N.F., Zerjatke, Thomas, Glauche, Ingmar, Munz, Clara M., Ge, Yan, Petzold, Andreas, Reinhardt, Susanne, Dahl, Andreas, Anstee, Natasha S., Bogeska, Ruzhica, Milsom, Michael D., Säwén, Petter, Wan, Haixia, Bryder, David, Roers, Axel, Gerbaulet, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7971128/
https://ncbi.nlm.nih.gov/pubmed/32302400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191284
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