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Continuous mitotic activity of primitive hematopoietic stem cells in adult mice
The proliferative activity of aging hematopoietic stem cells (HSCs) is controversially discussed. Inducible fluorescent histone 2B fusion protein (H2B-FP) transgenic mice are important tools for tracking the mitotic history of murine HSCs in label dilution experiments. A recent study proposed that p...
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| Veröffentlicht in: | J Exp Med |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Rockefeller University Press
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7971128/ https://ncbi.nlm.nih.gov/pubmed/32302400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191284 |
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