Continuous mitotic activity of primitive hematopoietic stem cells in adult mice

The proliferative activity of aging hematopoietic stem cells (HSCs) is controversially discussed. Inducible fluorescent histone 2B fusion protein (H2B-FP) transgenic mice are important tools for tracking the mitotic history of murine HSCs in label dilution experiments. A recent study proposed that p...

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Foilsithe in:J Exp Med
Main Authors: Morcos, Mina N.F., Zerjatke, Thomas, Glauche, Ingmar, Munz, Clara M., Ge, Yan, Petzold, Andreas, Reinhardt, Susanne, Dahl, Andreas, Anstee, Natasha S., Bogeska, Ruzhica, Milsom, Michael D., Säwén, Petter, Wan, Haixia, Bryder, David, Roers, Axel, Gerbaulet, Alexander
Formáid: Artigo
Teanga:Inglês
Foilsithe: Rockefeller University Press 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7971128/
https://ncbi.nlm.nih.gov/pubmed/32302400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191284
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