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Generation of reconstituted hemato-lymphoid murine embryos by placental transplantation into embryos lacking HSCs

In order to increase the contribution of donor HSC cells, irradiation and DNA alkylating agents have been commonly used as experimental methods to eliminate HSCs for adult mice. But a technique of HSC deletion for mouse embryo for increase contribution of donor cells has not been published. Here, we...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jeon, Hyojung, Asano, Keigo, Wakimoto, Arata, Kulathunga, Kaushalya, Tran, Mai Thi Nhu, Nakamura, Megumi, Yokomizo, Tomomasa, Hamada, Michito, Takahashi, Satoru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902833/
https://ncbi.nlm.nih.gov/pubmed/33623082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83652-9
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