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Generation of reconstituted hemato-lymphoid murine embryos by placental transplantation into embryos lacking HSCs

In order to increase the contribution of donor HSC cells, irradiation and DNA alkylating agents have been commonly used as experimental methods to eliminate HSCs for adult mice. But a technique of HSC deletion for mouse embryo for increase contribution of donor cells has not been published. Here, we...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Jeon, Hyojung, Asano, Keigo, Wakimoto, Arata, Kulathunga, Kaushalya, Tran, Mai Thi Nhu, Nakamura, Megumi, Yokomizo, Tomomasa, Hamada, Michito, Takahashi, Satoru
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902833/
https://ncbi.nlm.nih.gov/pubmed/33623082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83652-9
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