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Generation of reconstituted hemato-lymphoid murine embryos by placental transplantation into embryos lacking HSCs

In order to increase the contribution of donor HSC cells, irradiation and DNA alkylating agents have been commonly used as experimental methods to eliminate HSCs for adult mice. But a technique of HSC deletion for mouse embryo for increase contribution of donor cells has not been published. Here, we...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Jeon, Hyojung, Asano, Keigo, Wakimoto, Arata, Kulathunga, Kaushalya, Tran, Mai Thi Nhu, Nakamura, Megumi, Yokomizo, Tomomasa, Hamada, Michito, Takahashi, Satoru
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902833/
https://ncbi.nlm.nih.gov/pubmed/33623082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83652-9
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