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Hematopoiesis in steady-state versus stress: self-renewal, lineage fate choice, and the conversion of danger signals into cytokine signals in HSCs

Long-term hematopoietic stem cells (LT-HSCs) replenish the innate and adaptive immune compartments throughout life. While significant progress has defined the major transcription factors that regulate lineage specification, the architectural proteins that globally coordinate DNA methylation, histone...

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Détails bibliographiques
Auteur principal: Borghesi, Lisa
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135530/
https://ncbi.nlm.nih.gov/pubmed/25128551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400936
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