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Hematopoiesis in steady-state versus stress: self-renewal, lineage fate choice, and the conversion of danger signals into cytokine signals in HSCs

Long-term hematopoietic stem cells (LT-HSCs) replenish the innate and adaptive immune compartments throughout life. While significant progress has defined the major transcription factors that regulate lineage specification, the architectural proteins that globally coordinate DNA methylation, histone...

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Detalhes bibliográficos
Autor principal: Borghesi, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135530/
https://ncbi.nlm.nih.gov/pubmed/25128551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400936
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