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αβ versus γδ fate choice: counting the T-cell lineages at the branch point
Both αβ and γδ T cells develop in the thymus from a common progenitor. Historically distinguished by their T-cell receptor (TCR), these lineages are now defined on the basis of distinct molecular programs. Intriguingly, in many transgenic and knockout systems these programs are mismatched with the T...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031133/ https://ncbi.nlm.nih.gov/pubmed/20969592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2010.00947.x |
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