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αβ versus γδ fate choice: counting the T-cell lineages at the branch point

Both αβ and γδ T cells develop in the thymus from a common progenitor. Historically distinguished by their T-cell receptor (TCR), these lineages are now defined on the basis of distinct molecular programs. Intriguingly, in many transgenic and knockout systems these programs are mismatched with the T...

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Main Authors: Kreslavsky, Taras, Gleimer, Michael, Garbe, Annette I, von Boehmer, Harald
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031133/
https://ncbi.nlm.nih.gov/pubmed/20969592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2010.00947.x
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