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αβ versus γδ lineage choice at the first TCR-controlled checkpoint
αβ and γδ T-cells develop in the thymus from a common precursor. Although lineages initially were defined by the type of TCR they express, it soon became clear that the TCR type per se does not play a deterministic role in the lineage decision, since in various transgenic and knockout models, as wel...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861550/ https://ncbi.nlm.nih.gov/pubmed/20074925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2009.12.006 |
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