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Conversion of danger signals into cytokine signals by hematopoietic stem and progenitor cells for regulation of stress-induced hematopoiesis

During an infection, the body increases the output of mature immune cells to fight off the pathogen. Despite convincing evidence that hematopoietic stem and progenitor cells (HSPCs) can sense pathogens directly, how this contributes to hematopoietic cell output remains unknown. Here we have combined...

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Autors principals: Zhao, Jimmy L., Ma, Chao, O'Connell, Ryan M., Mehta, Arnav, DiLoreto, Race, Heath, James R., Baltimore, David
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119790/
https://ncbi.nlm.nih.gov/pubmed/24561084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.01.007
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