MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice

During inflammation and infection, hematopoietic stem and progenitor cells are stimulated to proliferate and differentiate into mature immune cells, especially of the myeloid lineage. MicroRNA-146a (miR-146a) is a critical negative regulator of inflammation. Deletion of miR-146a produces effects tha...

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Bibliographic Details
Main Authors: Zhao, Jimmy L, Rao, Dinesh S, O’Connell, Ryan M, Garcia-Flores, Yvette, Baltimore, David
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2013
Subjects:
Developmental Biology and Stem Cells
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660742/
https://ncbi.nlm.nih.gov/pubmed/23705069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00537
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