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MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice

During inflammation and infection, hematopoietic stem and progenitor cells are stimulated to proliferate and differentiate into mature immune cells, especially of the myeloid lineage. MicroRNA-146a (miR-146a) is a critical negative regulator of inflammation. Deletion of miR-146a produces effects tha...

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Detalhes bibliográficos
Main Authors: Zhao, Jimmy L, Rao, Dinesh S, O’Connell, Ryan M, Garcia-Flores, Yvette, Baltimore, David
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660742/
https://ncbi.nlm.nih.gov/pubmed/23705069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00537
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