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MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output

The production of blood cells depends on a rare hematopoietic stem-cell (HSC) population, but the molecular mechanisms underlying HSC biology remain incompletely understood. Here, we identify a subset of microRNAs (miRNAs) that is enriched in HSCs compared with other bone-marrow cells. An in vivo ga...

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Bibliografiske detaljer
Main Authors: O'Connell, Ryan M., Chaudhuri, Aadel A., Rao, Dinesh S., Gibson, William S. J., Balazs, Alejandro B., Baltimore, David
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922591/
https://ncbi.nlm.nih.gov/pubmed/20660734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009798107
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