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MicroRNA-34a perturbs B lymphocyte development by repressing the Forkhead Box Transcription Factor Foxp1

MicroRNAs (miRNAs) can influence lineage choice or affect critical developmental checkpoints during hematopoiesis. To search for a role of the recently described p53-induced microRNA, miR-34a, in hematopoiesis, we performed gain-of-function analysis in murine bone marrow. Constitutive expression of...

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Detalhes bibliográficos
Main Authors: Rao, Dinesh S., O’Connell, Ryan M., Chaudhuri, Aadel A., Garcia-Flores, Yvette, Geiger, Theresa L., Baltimore, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911227/
https://ncbi.nlm.nih.gov/pubmed/20598588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.06.013
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