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Rap1 signal modulators control the maintenance of hematopoietic progenitors in bone marrow and adult long‐term hematopoiesis

Adult long‐term hematopoiesis depends on sustaining hematopoietic stem/progenitor cells (HSPC) in bone marrow (BM) niches, where their balance of quiescence, self‐renewal, and hematopoietic differentiation is tightly regulated. Although various BM stroma cells that produce niche factors have been id...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Imai, Takahiko, Tanaka, Hiroki, Hamazaki, Yoko, Minato, Nagahiro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447830/
https://ncbi.nlm.nih.gov/pubmed/30767320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13974
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