Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A

MicroRNA-125b (miR-125b) is up-regulated in patients with leukemia. Overexpression of miR-125b alone in mice causes a very aggressive, transplantable myeloid leukemia. Before leukemia, these mice do not display elevation of white blood cells in the spleen or bone marrow; rather, the hematopoietic co...

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Detalhes bibliográficos
Main Authors: Chaudhuri, Aadel A., So, Alex Yick-Lun, Mehta, Arnav, Minisandram, Aarathi, Sinha, Nikita, Jonsson, Vanessa D., Rao, Dinesh S., O'Connell, Ryan M., Baltimore, David
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306721/
https://ncbi.nlm.nih.gov/pubmed/22366319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200677109
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