Regulation of APC development, immune response, and autoimmunity by Bach1/HO-1 pathway in mice

APCs are essential for innate and adaptive immunity as well as self-immune tolerance. Here, we show that the Cap'n'collar member Bach1 regulates the generation of APCs, specifically macrophages and dendritic cells, in mice. The impaired APC development in Bach1(−/−) mice was accompanied by...

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Detaylı Bibliyografya
Asıl Yazarlar: So, Alex Yick-Lun, Garcia-Flores, Yvette, Minisandram, Aarathi, Martin, Ayana, Taganov, Konstantin, Boldin, Mark, Baltimore, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2012
Konular:
Immunobiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448256/
https://ncbi.nlm.nih.gov/pubmed/22791292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-426247
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