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Regulation of APC development, immune response, and autoimmunity by Bach1/HO-1 pathway in mice
APCs are essential for innate and adaptive immunity as well as self-immune tolerance. Here, we show that the Cap'n'collar member Bach1 regulates the generation of APCs, specifically macrophages and dendritic cells, in mice. The impaired APC development in Bach1(−/−) mice was accompanied by...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448256/ https://ncbi.nlm.nih.gov/pubmed/22791292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-426247 |
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