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The impact of copy number variation on local gene expression in mouse hematopoietic stem/progenitor cells

The extent to which differences in germ line DNA copy number contribute to natural phenotypic variation is unknown. We analyzed the copy number content of the mouse genome to a sub-10 kb resolution. We identified over 1,300 copy number variant regions (CNVRs), most of which are < 10 kb in length,...

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Main Authors: Cahan, Patrick, Li, Yedda, Izumi, Masayo, Graubert, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728431/
https://ncbi.nlm.nih.gov/pubmed/19270704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.350
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