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Chromatin modifying enzymes as modulators of reprogramming

Generation of induced pluripotent stem cells (iPSCs) by somatic cell reprogramming involves global epigenetic remodeling(1). While several proteins are known to regulate chromatin marks associated with the distinct epigenetic states of cells before and after reprogramming(2,3), the role of specific...

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Detalhes bibliográficos
Main Authors: Onder, Tamer T., Kara, Nergis, Cherry, Anne, Sinha, Amit U., Zhu, Nan, Bernt, Kathrin M., Cahan, Patrick, Mancarci, Ogan. B., Unternaehrer, Juli, Gupta, Piyush B., Lander, Eric S., Armstrong, Scott A., Daley, George Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501145/
https://ncbi.nlm.nih.gov/pubmed/22388813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10953
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