Apoptotic Regulation by the Crk Adapter Protein Mediated by Interactions with Wee1 and Crm1/Exportin

Por Smith, Jesse J., Richardson, D. Ashley, Kopf, Jan, Yoshida, Minoru, Hollingsworth, Robert E., Kornbluth, Sally
Publicado em 2002

Wee1-Regulated Apoptosis Mediated by the Crk Adaptor Protein in Xenopus Egg Extracts

Por Smith, Jesse J., Evans, Erica K., Murakami, Monica, Moyer, Mary B., Moseley, M. Arthur, Woude, George Vande, Kornbluth, Sally
Publicado em 2000

ERBB4 is over-expressed in human colon cancer and enhances cellular transformation

Por Williams, Christopher S., Bernard, Jessica K., Demory Beckler, Michelle, Almohazey, Dana, Washington, Mary Kay, Smith, Jesse J., Frey, Mark R.
Publicado no Carcinogenesis (2015)

SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

Por Yoshizaki, Takeshi, Milne, Jill C., Imamura, Takeshi, Schenk, Simon, Sonoda, Noriyuki, Babendure, Jennie L., Lu, Juu-Chin, Smith, Jesse J., Jirousek, Michael R., Olefsky, Jerrold M.
Publicado em 2009

Myeloid translocation genes differentially regulate colorectal cancer programs

Por Parang, Bobak, Bradley, Amber M., Mittal, Mukul K., Short, Sarah P., Thompson, Joshua J., Barrett, Caitlyn W., Naik, Rishi D., Bilotta, Anthony J., Washington, Mary K., Revetta, Frank L., Smith, Jesse J., Chen, Xi, Wilson, Keith T., Hiebert, Scott W., Williams, Christopher S.
Publicado no Oncogene (2016)

Correction: Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial Sarcoma

Por Kawano, Satoshi, Grassian, Alexandra R., Tsuda, Masumi, Knutson, Sarah K., Warholic, Natalie M., Kuznetsov, Galina, Xu, Shanqin, Xiao, Yonghong, Pollock, Roy M., Smith, Jesse J., Kuntz, Kevin W., Ribich, Scott, Minoshima, Yukinori, Matsui, Junji, Copeland, Robert A., Tanaka, Shinya, Keilhack, Heike
Publicado no PLoS One (2017)

Synergistic Anti-Tumor Activity of EZH2 Inhibitors and Glucocorticoid Receptor Agonists in Models of Germinal Center Non-Hodgkin Lymphomas

Por Knutson, Sarah K., Warholic, Natalie M., Johnston, L. Danielle, Klaus, Christine R., Wigle, Tim J., Iwanowicz, Dorothy, Littlefield, Bruce A., Porter-Scott, Margaret, Smith, Jesse J., Moyer, Mikel P., Copeland, Robert A., Pollock, Roy M., Kuntz, Kevin W., Raimondi, Alejandra, Keilhack, Heike
Publicado no PLoS One (2014)

Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3

Por Jin, Lei, Galonek, Heidi, Israelian, Kristine, Choy, Wendy, Morrison, Michael, Xia, Yu, Wang, Xiaohong, Xu, Yihua, Yang, Yuecheng, Smith, Jesse J, Hoffmann, Ethan, Carney, David P, Perni, Robert B, Jirousek, Michael R, Bemis, Jean E, Milne, Jill C, Sinclair, David A, Westphal, Christoph H
Publicado em 2009

Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound

Por Mitchell, Lorna H., Drew, Allison E., Ribich, Scott A., Rioux, Nathalie, Swinger, Kerren K., Jacques, Suzanne L., Lingaraj, Trupti, Boriack-Sjodin, P. Ann, Waters, Nigel J., Wigle, Tim J., Moradei, Oscar, Jin, Lei, Riera, Tom, Porter-Scott, Margaret, Moyer, Mikel P., Smith, Jesse J., Chesworth, Richard, Copeland, Robert A.
Publicado no ACS Med Chem Lett (2015)

Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666

Por Duncan, Kenneth W., Rioux, Nathalie, Boriack-Sjodin, P. Ann, Munchhof, Michael J., Reiter, Lawrence A., Majer, Christina R., Jin, Lei, Johnston, L. Danielle, Chan-Penebre, Elayne, Kuplast, Kristy G., Porter Scott, Margaret, Pollock, Roy M., Waters, Nigel J., Smith, Jesse J., Moyer, Mikel P., Copeland, Robert A., Chesworth, Richard
Publicado no ACS Med Chem Lett (2015)

EPZ011989, A Potent, Orally-Available EZH2 Inhibitor with Robust in Vivo Activity

Por Campbell, John E., Kuntz, Kevin W., Knutson, Sarah K., Warholic, Natalie M., Keilhack, Heike, Wigle, Tim J., Raimondi, Alejandra, Klaus, Christine R., Rioux, Nathalie, Yokoi, Akira, Kawano, Satoshi, Minoshima, Yukinori, Choi, Hyeong-Wook, Porter Scott, Margaret, Waters, Nigel J., Smith, Jesse J., Chesworth, Richard, Moyer, Mikel P., Copeland, Robert A.
Publicado no ACS Med Chem Lett (2015)

Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo

Por Smith, Jesse J, Kenney, Renée Deehan, Gagne, David J, Frushour, Brian P, Ladd, William, Galonek, Heidi L, Israelian, Kristine, Song, Jeffrey, Razvadauskaite, Giedre, Lynch, Amy V, Carney, David P, Johnson, Robin J, Lavu, Siva, Iffland, Andre, Elliott, Peter J, Lambert, Philip D, Elliston, Keith O, Jirousek, Michael R, Milne, Jill C, Boss, Olivier
Publicado em 2009

Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor

Por Mitchell, Lorna H., Boriack-Sjodin, P. Ann, Smith, Sherri, Thomenius, Michael, Rioux, Nathalie, Munchhof, Michael, Mills, James E., Klaus, Christine, Totman, Jennifer, Riera, Thomas V., Raimondi, Alejandra, Jacques, Suzanne L., West, Kip, Foley, Megan, Waters, Nigel J., Kuntz, Kevin W., Wigle, Tim J., Scott, Margaret Porter, Copeland, Robert A., Smith, Jesse J., Chesworth, Richard
Publicado no ACS Med Chem Lett (2015)

Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor

Por Daigle, Scott R., Olhava, Edward J., Therkelsen, Carly A., Majer, Christina R., Sneeringer, Christopher J., Song, Jeffrey, Johnston, L. Danielle, Scott, Margaret Porter, Smith, Jesse J., Xiao, Yonghong, Jin, Lei, Kuntz, Kevin W., Chesworth, Richard, Moyer, Mikel P., Bernt, Kathrin M., Tseng, Jen-Chieh, Kung, Andrew L., Armstrong, Scott A., Copeland, Robert A., Richon, Victoria M., Pollock, Roy M.
Publicado em 2011

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP

Por Walker, Amy K., Yang, Fajun, Jiang, Karen, Ji, Jun-Yuan, Watts, Jennifer L., Purushotham, Aparna, Boss, Olivier, Hirsch, Michael L., Ribich, Scott, Smith, Jesse J., Israelian, Kristine, Westphal, Christoph H., Rodgers, Joseph T., Shioda, Toshi, Elson, Sarah L., Mulligan, Peter, Najafi-Shoushtari, Hani, Black, Josh C., Thakur, Jitendra K., Kadyk, Lisa C., Whetstine, Johnathan R., Mostoslavsky, Raul, Puigserver, Pere, Li, Xiaoling, Dyson, Nicholas J., Hart, Anne C., Näär, Anders M.
Publicado em 2010

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Por Milne, Jill C., Lambert, Philip D., Schenk, Simon, Carney, David P., Smith, Jesse J., Gagne, David J., Jin, Lei, Boss, Olivier, Perni, Robert B., Vu, Chi B., Bemis, Jean E., Xie, Roger, Disch, Jeremy S., Ng, Pui Yee, Nunes, Joseph J., Lynch, Amy V., Yang, Hongying, Galonek, Heidi, Israelian, Kristine, Choy, Wendy, Iffland, Andre, Lavu, Siva, Medvedik, Oliver, Sinclair, David A., Olefsky, Jerrold M., Jirousek, Michael R., Elliott, Peter J., Westphal, Christoph H.
Publicado em 2007