ErbB2 Stabilizes Epidermal Growth Factor Receptor (EGFR) Expression via Erk and Sprouty2 in Extracellular Matrix-detached Cells

per Grassian, Alexandra R., Schafer, Zachary T., Brugge, Joan S.
Publicat 2011

Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation

per Grassian, Alexandra R., Metallo, Christian M., Coloff, Jonathan L., Stephanopoulos, Gregory, Brugge, Joan S.
Publicat 2011

Antioxidant and Oncogene Rescue of Metabolic Defects Caused by Loss of Matrix Attachment

per Schafer, Zachary T., Grassian, Alexandra R., Song, Loling, Jiang, Zhenyang, Gerhart-Hines, Zachary, Irie, Hanna Y., Gao, Sizhen, Puigserver, Pere, Brugge, Joan S.
Publicat 2009

Isocitrate Dehydrogenase (IDH) Mutations Promote a Reversible ZEB1/MicroRNA (miR)-200-dependent Epithelial-Mesenchymal Transition (EMT)

per Grassian, Alexandra R., Lin, Fallon, Barrett, Rosemary, Liu, Yue, Jiang, Wei, Korpal, Manav, Astley, Holly, Gitterman, Daniel, Henley, Thomas, Howes, Rob, Levell, Julian, Korn, Joshua M., Pagliarini, Raymond
Publicat 2012

Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial Sarcoma

per Kawano, Satoshi, Grassian, Alexandra R., Tsuda, Masumi, Knutson, Sarah K., Warholic, Natalie M., Kuznetsov, Galina, Xu, Shanqin, Xiao, Yonghong, Pollock, Roy M., Smith, Jesse S., Kuntz, Kevin K., Ribich, Scott, Minoshima, Yukinori, Matsui, Junji, Copeland, Robert A., Tanaka, Shinya, Keilhack, Heike
Publicat a PLoS One (2016)

Correction: Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial Sarcoma

per Kawano, Satoshi, Grassian, Alexandra R., Tsuda, Masumi, Knutson, Sarah K., Warholic, Natalie M., Kuznetsov, Galina, Xu, Shanqin, Xiao, Yonghong, Pollock, Roy M., Smith, Jesse J., Kuntz, Kevin W., Ribich, Scott, Minoshima, Yukinori, Matsui, Junji, Copeland, Robert A., Tanaka, Shinya, Keilhack, Heike
Publicat a PLoS One (2017)

IDH1 Mutations Alter Citric Acid Cycle Metabolism and Increase Dependence on Oxidative Mitochondrial Metabolism

per Grassian, Alexandra R., Parker, Seth J., Davidson, Shawn M., Divakarun, Ajit S., Green, Courtney R., Zhang, Xiamei, Slocum, Kelly L., Pu, Minying, Lin, Fallon, Vickers, Chad, Joud-Caldwell, Carol, Chung, Franklin, Yin, Hong, Handly, Erika D., Straub, Christopher, Growney, Joseph D., Vander Heiden, Matthew G., Murphy, Anne N., Pagliarini, Raymond, Metallo, Christian M.
Publicat a Cancer Res (2014)

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

per Locasale, Jason W., Grassian, Alexandra R., Melman, Tamar, Lyssiotis, Costas A., Mattaini, Katherine R., Bass, Adam J., Heffron, Gregory, Metallo, Christian M., Muranen, Taru, Sharfi, Hadar, Sasaki, Atsuo T., Anastasiou, Dimitrios, Mullarky, Edouard, Vokes, Natalie I., Sasaki, Mika, Beroukhim, Rameen, Stephanopoulos, Gregory, Ligon, Azra H., Meyerson, Matthew, Richardson, Andrea L, Chin, Lynda, Wagner, Gerhard, Asara, John M, Brugge, Joan S., Cantley, Lewis C., Vander Heiden, Matthew G.
Publicat 2011

Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation

per Thomenius, Michael J., Totman, Jennifer, Harvey, Darren, Mitchell, Lorna H., Riera, Thomas V., Cosmopoulos, Kat, Grassian, Alexandra R., Klaus, Christine, Foley, Megan, Admirand, Elizabeth A., Jahic, Haris, Majer, Christina, Wigle, Tim, Jacques, Suzanne L., Gureasko, Jodi, Brach, Dorothy, Lingaraj, Trupti, West, Kip, Smith, Sherri, Rioux, Nathalie, Waters, Nigel J., Tang, Cuyue, Raimondi, Alejandra, Munchhof, Michael, Mills, James E., Ribich, Scott, Porter Scott, Margaret, Kuntz, Kevin W., Janzen, William P., Moyer, Mikel, Smith, Jesse J., Chesworth, Richard, Copeland, Robert A., Boriack-Sjodin, P. Ann
Publicat a PLoS One (2018)