Selective Inhibitors of Protozoan Protein N-myristoyltransferases as Starting Points for Tropical Disease Medicinal Chemistry Programs

Por Bell, Andrew S., Mills, James E., Williams, Gareth P., Brannigan, James A., Wilkinson, Anthony J., Parkinson, Tanya, Leatherbarrow, Robin J., Tate, Edward W., Holder, Anthony A., Smith, Deborah F.
Publicado em 2012

Continuing analysis of microRNA origins: Formation from transposable element insertions and noncoding RNA mutations

Por Roberts, Justin T, Cooper, Elvera A, Favreau, Connor J, Howell, Jacob S, Lane, Lee G, Mills, James E, Newman, Derrick C, Perry, Tabitha J, Russell, Meaghan E, Wallace, Brittany M, Borchert, Glen M
Publicado em 2013

Discovery of a First-In-Class Small Molecule Antagonist against the Adrenomedullin-2 Receptor: Structure–Activity Relationships and Optimization

Por Zirimwabagabo, Jean-Olivier, Jailani, Ameera B. A., Avgoustou, Paris, Tozer, Matthew J., Gibson, Karl R., Glossop, Paul A., Mills, James E. J., Porter, Roderick A., Blaney, Paul, Wang, Ning, Skerry, Timothy M., Richards, Gareth O., Harrity, Joseph P. A.
Publicado no J Med Chem (2021)

Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor

Por Mitchell, Lorna H., Boriack-Sjodin, P. Ann, Smith, Sherri, Thomenius, Michael, Rioux, Nathalie, Munchhof, Michael, Mills, James E., Klaus, Christine, Totman, Jennifer, Riera, Thomas V., Raimondi, Alejandra, Jacques, Suzanne L., West, Kip, Foley, Megan, Waters, Nigel J., Kuntz, Kevin W., Wigle, Tim J., Scott, Margaret Porter, Copeland, Robert A., Smith, Jesse J., Chesworth, Richard
Publicado no ACS Med Chem Lett (2015)

Discovery of a First-in-Class Potent Small Molecule Antagonist against the Adrenomedullin-2 Receptor

Por Avgoustou, Paris, Jailani, Ameera B. A., Zirimwabagabo, Jean-Olivier, Tozer, Matthew J., Gibson, Karl R., Glossop, Paul A., Mills, James E. J., Porter, Roderick A., Blaney, Paul, Bungay, Peter J., Wang, Ning, Shaw, Alice P., Bigos, Kamilla J. A., Holmes, Joseph L., Warrington, Jessica I., Skerry, Timothy M., Harrity, Joseph P. A., Richards, Gareth O.
Publicado no ACS Pharmacol Transl Sci (2020)

Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation

Por Thomenius, Michael J., Totman, Jennifer, Harvey, Darren, Mitchell, Lorna H., Riera, Thomas V., Cosmopoulos, Kat, Grassian, Alexandra R., Klaus, Christine, Foley, Megan, Admirand, Elizabeth A., Jahic, Haris, Majer, Christina, Wigle, Tim, Jacques, Suzanne L., Gureasko, Jodi, Brach, Dorothy, Lingaraj, Trupti, West, Kip, Smith, Sherri, Rioux, Nathalie, Waters, Nigel J., Tang, Cuyue, Raimondi, Alejandra, Munchhof, Michael, Mills, James E., Ribich, Scott, Porter Scott, Margaret, Kuntz, Kevin W., Janzen, William P., Moyer, Mikel, Smith, Jesse J., Chesworth, Richard, Copeland, Robert A., Boriack-Sjodin, P. Ann
Publicado no PLoS One (2018)