Discovery of a Selective TRPM8 Antagonist with Clinical Efficacy in Cold-Related Pain

Autor Andrews, Mark D., af Forselles, Kerry, Beaumont, Kevin, Galan, Sébastien R. G., Glossop, Paul A., Grenie, Mathilde, Jessiman, Alan, Kenyon, Amy S., Lunn, Graham, Maw, Graham, Owen, Robert M., Pryde, David C., Roberts, Dannielle, Tran, Thien Duc
Vydáno v ACS Med Chem Lett (2015)

Discovery of a First-In-Class Small Molecule Antagonist against the Adrenomedullin-2 Receptor: Structure–Activity Relationships and Optimization

Autor Zirimwabagabo, Jean-Olivier, Jailani, Ameera B. A., Avgoustou, Paris, Tozer, Matthew J., Gibson, Karl R., Glossop, Paul A., Mills, James E. J., Porter, Roderick A., Blaney, Paul, Wang, Ning, Skerry, Timothy M., Richards, Gareth O., Harrity, Joseph P. A.
Vydáno v J Med Chem (2021)

Discovery of a First-in-Class Potent Small Molecule Antagonist against the Adrenomedullin-2 Receptor

Autor Avgoustou, Paris, Jailani, Ameera B. A., Zirimwabagabo, Jean-Olivier, Tozer, Matthew J., Gibson, Karl R., Glossop, Paul A., Mills, James E. J., Porter, Roderick A., Blaney, Paul, Bungay, Peter J., Wang, Ning, Shaw, Alice P., Bigos, Kamilla J. A., Holmes, Joseph L., Warrington, Jessica I., Skerry, Timothy M., Harrity, Joseph P. A., Richards, Gareth O.
Vydáno v ACS Pharmacol Transl Sci (2020)