SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

SIRT1 is a prominent member of a family of NAD(+)-dependent enzymes and affects a variety of cellular functions ranging from gene silencing, regulation of the cell cycle and apoptosis, to energy homeostasis. In mature adipocytes, SIRT1 triggers lipolysis and loss of fat content. However, the potenti...

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Главные авторы: Yoshizaki, Takeshi, Milne, Jill C., Imamura, Takeshi, Schenk, Simon, Sonoda, Noriyuki, Babendure, Jennie L., Lu, Juu-Chin, Smith, Jesse J., Jirousek, Michael R., Olefsky, Jerrold M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643824/
https://ncbi.nlm.nih.gov/pubmed/19103747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00705-08
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