SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

SIRT1 is a prominent member of a family of NAD(+)-dependent enzymes and affects a variety of cellular functions ranging from gene silencing, regulation of the cell cycle and apoptosis, to energy homeostasis. In mature adipocytes, SIRT1 triggers lipolysis and loss of fat content. However, the potenti...

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Main Authors: Yoshizaki, Takeshi, Milne, Jill C., Imamura, Takeshi, Schenk, Simon, Sonoda, Noriyuki, Babendure, Jennie L., Lu, Juu-Chin, Smith, Jesse J., Jirousek, Michael R., Olefsky, Jerrold M.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643824/
https://ncbi.nlm.nih.gov/pubmed/19103747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00705-08
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