SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity

Chronic inflammation is an important etiology underlying obesity-related disorders such as insulin resistance and type 2 diabetes, and recent findings indicate that the macrophage can be the initiating cell type responsible for this chronic inflammatory state. The mammalian silent information regula...

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Detalhes bibliográficos
Main Authors: Yoshizaki, Takeshi, Schenk, Simon, Imamura, Takeshi, Babendure, Jennie L., Sonoda, Noriyuki, Bae, Eun Ju, Oh, Da Young, Lu, Min, Milne, Jill C., Westphal, Christoph, Bandyopadhyay, Gautam, Olefsky, Jerrold M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838524/
https://ncbi.nlm.nih.gov/pubmed/19996381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00417.2009
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