SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

SIRT1 is a prominent member of a family of NAD(+)-dependent enzymes and affects a variety of cellular functions ranging from gene silencing, regulation of the cell cycle and apoptosis, to energy homeostasis. In mature adipocytes, SIRT1 triggers lipolysis and loss of fat content. However, the potenti...

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Bibliographic Details
Main Authors: Yoshizaki, Takeshi, Milne, Jill C., Imamura, Takeshi, Schenk, Simon, Sonoda, Noriyuki, Babendure, Jennie L., Lu, Juu-Chin, Smith, Jesse J., Jirousek, Michael R., Olefsky, Jerrold M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643824/
https://ncbi.nlm.nih.gov/pubmed/19103747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00705-08
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